Noise properties of proton density fat fraction estimated using chemical shift-encoded MRI

Estimating of hepatic fat amount using MRI proton density fat fraction in a real practice setting

The recently developed magnetic resonance imaging (MRI) proton density fat fraction (PDFF) allows measurement of the fat in all segments of hepatic tissue. However, it is time consuming and inconvenient to measure each segment repeatedly. Moreover, volume of each segment also should be adjusted with arithmetic mean of the selected segments when total amount of liver fat is estimated. Therefore,...

Measurement of interscapular brown adipose tissue of mice in differentially housed temperatures by chemical-shift-encoded water-fat MRI.

PURPOSE To determine differences in fat-signal fraction (FF) from chemical-shift-encoded water-fat MRI of interscapular BAT in mice housed at different ambient temperatures (Ta ). MATERIALS AND METHODS C57BL/6J male mice (8 weeks old) were singly housed at 16°C, 23°C, or 30°C (n = 16/group) for 4 weeks. Measures included food intake, body weight (both measured weekly) and body composition (at...

Proton density fat-fraction: a standardized MR-based biomarker of tissue fat concentration.

Diagnostic Value of MRI Proton Density Fat Fraction for Assessing Liver Steatosis in Chronic Viral C Hepatitis

OBJECTIVE To assess the diagnostic performance of a T1-independent, T2*-corrected multiecho magnetic resonance imaging (MRI) technique for the quantification of hepatic steatosis in a cohort of patients affected by chronic viral C hepatitis, using liver biopsy as gold standard. METHODS Eighty-one untreated patients with chronic viral C hepatitis were prospectively enrolled. All included patie...

Three-dimensional phase-encoded chemical shift MRI in the presence of inhomogeneous fields.

A pulse sequence consisting of an excitation pulse and two adiabatic full-passage pulses with scaled relative peak amplitudes is combined with phase encoding to recover chemical shift information within 3D images in a 1D inhomogeneous static magnetic field with a matched rf field gradient. The results are discussed in the context of ex situ magnetic resonance and imaging. The future directions ...